14 novembre 2014, 9h-18h30, à l’Institut de Recherche contre le Cancer de Montpellier, Campus Val d’Aurelle, 208 rue des apothicaires, Montpellier

Inscription en ligne obligatoire

Consulter le programme complet sur le site internet de SIRIC Montpellier Cancer 

Programme :

9h00 Workshop Opening: Marc Ychou, David Azria and André Pèlegrin, Montpellier, France
Radiotoxicity: Clinical context – Chairman: Mahmut Oszahin, Lausanne, Switzerland
9h20 Lecture: The importance of considering patients at risk of developing late side‐effects after curative intent radiotherapy – Catharine M.L. West, Manchester, UK
SESSION 1: DNA Damage – Chairmen : Claude Sardet and David Azria, Montpellier, France
10h10 Lecture: ‘Unexpected, new functions of BRCA1’ – David Livingston, Boston, US
11h Coffee‐Break
11h30 Genotoxic stress induced reprogramming of gene expression – Bijan Sobhian, Montpellier, France
12h00 Interplay between DNA damage tolerance and DNA damage response and its implications in the resistance to DNA damaging agents – Domenico Maiorano, Montpellier, France
12h30 Fanconi anemia proteins at the crossroads of DNA replication and co‐transcriptional processes – Angelos Constantinou, Montpellier, France

13h00 Lunch Buffet

SESSION 2: Immunological mechanisms of radiotoxicity – Chairmen : Céline Bourgier and Jean‐François Eliaou, Montpellier, France
14h15 Using local radiotherapy to induce systemic anti‐tumor immunity – Claire Vanpouille‐Box, NY, US
15h00 TRAIL/TNFSF10 is functionally and genetically associated with human T4EM‐lymphocyte radiosensitivity – Annette Schmitz, Paris, France
15h30 Long‐term side effects after radiotherapy and immunology: the key points – Jean‐François Eliaou, Montpellier, France

16h00 Coffee‐ Break

SESSION 3: Reactive Oxygen Species (ROS) and radiotherapy – Chairmen : François Paris, Nantes, and Guillaume Bossis, Montpellier, France
16h30 ROS and thyroid radiocarcinogenesis – Corinne Dupuy, Paris, France
17h00 Quantitative proteomic approach to identify hypersensitive patients to curative intent radiotherapy – Jérôme Lacombe, Montpellier, France
17h30 Autoimmunity, oxidative stress, and fibrosis – Philippe Guilpain, Montpellier, France
18h00 Redox control of the SUMO pathway in cancer – Guillaume Bossis, Montpellier, France
18h30 Closing Remarks: David Azria and André Pèlegrin, Montpellier, France