Management of colon cancer patients: A comprehensive analysis of the absence of multidisciplinary team meetings in two French departments

Clinicals and research in hepatology and gastroenterology, March 2021

Anne-Sophie Foucan, Pascale Grosclaude, Véronique Bousser, Eric Bauvin, Denis Smith, Céline Andre-Fardeau, Laetitia Daubisse-Marliac, Simone Mathoulin-Pelissier, Brice Amadeo, Gaëlle Coureau

doi: 10.1016/j.clinre.2020.02.020


Background: The care management of colorectal cancers has evolved, particularly since the implementation of multidisciplinary team meetings (MDTm). The aim of this study was to identify factors associated with the non-presentation of colon cancer patients in MDTm (no-MDTm) and to assess the association between no-MDTm and the diagnostic and therapeutic care management, in two areas in France, in 2010.

Methods: Patients over 18 years diagnosed for invasive colon cancer in Gironde and Tarn during 2010 were included from the cancer registries of these two departments. We used five indicators to evaluate the care management of colon cancer patients (about diagnosis, treatment and selection of patients for chemotherapy).

Results: No-MDTm patients were more likely to die early after diagnosis (OR=2.94, 95% CI=[1.52-5.66]). Elderly patients and those living in more disadvantaged areas were less often presented in MDTm (OR≥85years=2.10, 95% CI=[1.06-4.18]; OREDIQ4-Q5=1.96, 95% CI=[1.23-3.14]). After adjusting for patient-related variables (age, comorbidities, deprivation) and tumor (stage at diagnosis), we found that thoracic CT scan was less often performed among no-MDTm patients (OR=0.40, 95% CI=[0.24-0.65]). There was no association between the absence of MDTm and the therapeutic care management indicators.

Conclusion: In conclusion, therapeutic care management was not associated with the absence of MDTm but with patient and tumor characteristics, including age, comorbidities and level of deprivation, that influence the non-presentation in MDTm.

Keywords: Cancer registry; Colon cancer; European Deprivation Index; Multidisciplinary team meeting; Therapeutic care management.