SYNVEC

Localization
SynVec, UFR de Pharmacie, Université de Bordeaux 146 Rue Léo Saignat, 33000 Bordeaux.
DEMANDE D'UTILISATION

Contact

Description

SynVec is a Technologic Transfer Unit of ADERA (Association for the development of teaching and research for Aquitania universities, research centers and companies). The creation of SynVec was encouraged by the research and technology transfer department of the Aquitania Council, and the European Regional Development Funds (ERDF) which certifies its ability to respond professionally to the needs of customers.

SynVec allows access to technological innovation for private companies. Indeed, our expertise is based on the expert knowledge and technical ability provided by the different teams of the research unit U869 of INSERM implanted in the University of Bordeaux. This expertise allows us to provide supports for cosmetics, pharmaceuticals and food industries in the field of chemistry and chemical biology.

R&D programs for which we are in charge are drived under strict confidentiality. This operating mode gives us a real reactivity and thus guarantees short deadlines to meet your needs.

At the interface between academic research and industry, SynVec allows its partners to:

  • Have significant and efficient research resources.
  • Use recognized scientific expertise and specific knowledge.
  • Develop new applications trough our new therapeutics vectors and new molecules.

Our team composed by well trained technicians and PhD in Chemistry is in charge of every request in order to ensure speed and quality of our service. Through our chemical synthesis and vectorisation expertise, SynVec uses a set of complementary technologies which are essential for efficient drug delivery.

Activity

R&D Programs : Custom synthesis of therapeutic and chemical vectors, Custom synthesis and development of fluorescent dyes, and fluorescent labeling systems and Custom synthesis and development of peptides and enzymatic substrates. Custom synthesis: Classic organic synthesis, Heterocyclic and muti-stapes, Peptides custom synthesis and synthesis on a solid support, Pharmaceutical impurities custom synthesis, Scale-up synthesis from milligram quantities to gram and kilogram quantities, Synthesis of modified nucleosides and phosphoramidites Molecules purification and identification: Purifications by chromatography with silica gel and with HPLC column, Analysis by HPLC, NMR, IR and FT-IR spectroscopy and UV and fluorescence spectroscopy.

Infrastructure and equipment

  • Chemical Synthesis laboratory
  • NMR Bruker Avance 300 MHz
  • HPLC (analytic and preparative)
  • Spectrometer UV, IR
  • Fluorescence spectrometer
  • DSC
  • Automatic peptide synthesizer

Publication

M-A. ALOUINI, E-F. MOUSTOIFA, S. FERY-FORGUES, T. BERTHELOT, A. BARTEGI, S. ALBENQUE-RUBIO, and G. DELERIS. D ; Interaction of Fluorescently Labeled Triethyleneglycol and Peptide Derivatives with b-Cyclodextrin ; ChemPhysChem, 2014, 15 (3), 444-457. C. SOUM, S. ALBENQUE-RUBIO , S. FERY-FORGUES, G. DELERIS, M-A. ALOUINI, and T. BERTHELOT ; Supramolecular Peptide/Surface Assembly for Monitoring Proteinase Activity and Cancer Diagnosis ; Applied Materials and Interfaces, 2015, 7 (31), 16967–16975.