BRIO is managed by a Director (Pr Pierre-Louis Soubeyran) and a Deputy Director (Pr François-Xavier Mahon). The Director and Deputy Director are supported by the management team which includes the General Manager (Damien Dessis) with two staff members, a head of Project Management (Frédéric Elustondo) and a Scientific Communication Manager (Gwénola Maguelonne).
Pierre Soubeyran, MD, PhD, BRIO Director, is Professor of Medicine in the Medical Oncology Department at Institut Bergonié, Regional Cancer Center in Bordeaux, France. He received his Medical Degree in 1989 from the Bordeaux Segalen University, his board certifications in 1989 and his PhD Degree in 1996. His fields of interest are non-Hodgkin’s lymphomas, molecular biology and cancer in the elderly. Head of the team “Molecular Mechanisms of Response to Treatment”, INSERM U916 Unit Validation and Identification of New Targets in Oncology (VINCO), since 2011, Pr Soubeyran is an active member of a number of professional groups including the American Society of Clinical Oncology (ASCO, since 2001), American Society of Hematology (ASH, since 1993), European Society of Medical Oncology (ESMO, since 1990), European Society of Therapeutic Radiology and Oncology (ESTRO, since 1987), International Society of Geriatric Oncology (SIOG, since 2002).
- Head of Clinical Research at Institut Bergonié (2002-2011) and President of the Internal Scientific Council of Institut Bergonié (2005-2011).
- Member of the Scientific Steering Committee of Cancéropôle du Grand Sud-Ouest since 2007.
- Member of the Scientific Steering Committee of the INCa-labelled Bordeaux Cancer Data Centre (Centre de Traitement de Données – CTD).
- Co-Coordinator of the INCa-labelled Coordination Unit of Geriatric Oncology (UCOG).
- Co-Coordinator of the regional “Malignant Haematology Group” and “Geriatric Oncology Group” from the Réseau de Cancérologie d’Aquitaine.
- Member of the Committee for Biomedical and Public Health research (Comité de la Recherche en matière Biomédicale et de Santé publique – CRBS) of the University Hospital Center of Bordeaux.
- Member of pharmaceutical company advisory boards focused on Geriatric Oncology (Chugai, Roche, Celgene, Amgen).
François-Xavier Mahon, MD, PhD, BRIO Deputy Director, is Professor of Hematology, Director of the Leukemic Haematopoiesis, Bordeaux University and Therapeutic Targets Laboratory, INSERM U1035. He received his Medical Degree in 1993 from the Bordeaux Segalen University and his PhD in 1997. He completed a research fellowship at Imperial College of London in 1999 and became Professor of medicine in 2002. His fields of interest are oncogenes such as BCR-ABL1, tyrosine kinase, the action and resistance of tyrosine kinase inhibitors, leukemogenesis, chronic myeloid leukemia, myeloproliferative disorders and Leukemic Stem Cells. He is a referee for journals such as Leukemia, Blood, Stem Cell, Experimental Haematology, Haematologica, European Journal of Hematology, European Cytokine Network, Bulletin du Cancer, Oncogene, Cancer and Clinical Cancer Research. Pr Mahon is an active member of a number of professional groups including American Society of Hematology (ASH), European Haematology Association (EHA), French Society of Haematology.
- Member of the Board of Direction de la Recherche Clinique et de l’Innovation (DRCI) of Bordeaux University Hospital Center.
- EICML Group investigations (European Investigation of Chronic Myeloid Leukemia)
- The European LeukemiaNet, in charge of one the The European Treatment Outcome Study (EUTOS) programs
- iCMLf (international CML foundation) Scientific Advisory Committee
- President of the French intergroup of CML investigators (FI-LMC)
Dr Paolo Meoni, MPharm, MSc, PhD. As the General Secretary of BRIO, Paolo Meoni is responsible for the overall management of activities initiated by the SIRIC and particularly for aspects related to program management, partnerships, communication, and technology transfer. Pharmacist, Pharmacologist and trained in pharmaco-economy and business management, Paolo started his career as a researcher in several European universities including the University of Florence, London School of Pharmacy, University of Birmingham and University of Paris VI between others. He then moved on to the industrial sector and held various positions in pharma and biotech companies (Wyeth-Ayerst, Euroscreen, Ablynx) before taking up the responsibility of Drug Discovery and Development competency area manager at the Council for Scientific and Industrial Research of South Africa. Before joining BRIO, Paolo worked as a consultant in various projects serving the private and public sector including the definition of the national biotechnology development strategy for Tunisia.
Frédéric Elustondo,Head of Project Management BRIO, is in charge of SIRIC projects management and monitoring, in collaboration with BRIO program coordinators and researchers. Frédéric worked for 10 years in the pharmaceutical industry as a medicinal chemist. He worked on cancer research for the past nine years at Cancer Research Technology and RedX Pharma where he conducted and managed several multidisciplinary projects in oncology. Frederic holds a Master’s degree in Material, Structural and Molecular Processes from the University of Bordeaux I, and a PhD in organic chemistry, “New methodology toward the synthesis of polycyclic ethers natural products”, from the University of Nottingham. In 2002 he won the Pfizer / Nottingham award for the best research project.
Gwénola Maguelonne, Scientific Communication Manager BRIO, is responsible for the implementation, coordination and monitoring of the scientific knowledge dissemination program in collaboration with other members of BRIO. Gwénola mainly worked in the field of communication and scientific mediation. She worked two years designing and programming scientific culture events at Cap Sciences (Centre for Scientific, Technical and Industrial Culture). She then worked for a year and a half at Médias-Cité (resource center for multimedia purposes) as responsible for the development of “digital territory project”. Gwénola holds a Bachelor’s degree in Animal Biology from the University Paris Sud (Paris 11), a Master’s degree in Oceanography and Marine Environments from the University Pierre et Marie Curie (Paris 6) and a Master’s degree in History, Philosophy and Science of Mediation from the University Montaigne Bordeaux.